A needle is used to remove and test CSF from the space that contains your spinal cord and nerve roots. The spinal cord runs through most of your spine. It carries messages between your brain and the rest of your body. A lumbar puncture is usually done near the base of your spine, below where the spinal cord ends. Local anesthesia will be used. The needle enters the space but does not touch the spinal cord. There is a risk of a headache or upset stomach after the procedure. This may occur because of a CSF leak under the skin. But this risk can be decreased with bed rest and drinking enough fluids during the first 24 hours after the test. Other risks include back ache, infection, bleeding, or other rare complications. Lumbar puncture is essential for diagnosing many nervous system conditions. It is advised when the benefits outweigh the risks. Sometimes this procedure is done with ultrasound or fluoroscopic guidance.