If the brachial plexus is pinched because of TOS (neurogenic TOS), you can have weakness in the hand and wrist. You may also have numbness in the small finger. In cases of TOS that pinch the veins, a blood clot can form in a vein in your arm. This blocks blood flow and may make your arm very swollen. The clot may also move to the lungs and cause a pulmonary embolism. This is a blood clot in an artery in your lung. Or a clot can move somewhere else in your body. You may need to take blood-thinner medicine to prevent clotting. You may need a procedure to remove the clot using a thin tube (catheter) inserted through a vein.
A blood clot may also form in one of the arteries of your arm. This may cause a sudden decrease in blood flow to your arm. The clot may be treated with blood thinners or a catheter inserted through an artery. In some cases, surgery may be done to remove the clot.