COPD (chronic obstructive pulmonary disease) is a health problem that keeps your lungs from working as they should. The lungs' job is to get oxygen to the body. Oxygen is an important gas your body needs to work correctly. The air you breathe in contains oxygen. Inside the lungs, air moves through tubes called airways. In healthy airways, air moves in and out easily. With COPD, lungs and airways are damaged. When lungs are damaged, it takes more work to get air into the lungs. Poor airflow means the body can't get the oxygen it needs. You may also have higher levels of carbon dioxide. Carbon dioxide is a waste product of breathing. COPD also causes inflammation in the lungs. These things can also lead to fatigue.
With COPD, lung damage is usually from breathing in irritants over a long period of time. The main irritant that causes COPD is cigarette smoke. Other irritants are pollution, dust, fumes, and chemicals.